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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NADSYN1
All Species:
29.39
Human Site:
S399
Identified Species:
58.79
UniProt:
Q6IA69
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IA69
NP_060631.2
706
79285
S399
R
T
I
V
N
Q
I
S
Y
T
P
Q
D
P
R
Chimpanzee
Pan troglodytes
XP_001174076
707
79303
S400
R
T
I
V
N
Q
I
S
Y
T
P
Q
D
P
R
Rhesus Macaque
Macaca mulatta
XP_001098992
706
78752
S399
R
T
I
V
N
Q
I
S
Y
T
P
Q
D
P
R
Dog
Lupus familis
XP_540795
720
80313
S427
R
A
I
V
D
Q
L
S
Y
T
P
Q
D
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q711T7
725
81634
S399
Q
N
L
V
D
E
S
S
Y
T
P
Q
D
P
R
Rat
Rattus norvegicus
Q812E8
725
81493
S399
Q
N
L
V
D
E
S
S
Y
T
P
Q
D
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506088
707
79645
A399
R
K
I
V
Y
N
D
A
Y
T
P
E
D
P
R
Chicken
Gallus gallus
Q5ZMA6
707
79208
T399
R
K
I
V
H
D
E
T
Y
I
P
E
D
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092723
694
78393
S398
Q
R
V
V
G
D
S
S
Y
R
P
Q
D
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYA0
787
87596
D399
R
Q
L
L
A
D
S
D
Y
T
P
D
N
A
A
Honey Bee
Apis mellifera
XP_392994
727
82171
E394
R
K
I
V
G
D
F
E
Y
V
P
T
D
P
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38795
714
80667
T399
I
K
D
V
R
K
I
T
R
S
G
D
D
W
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
92.9
81.3
N.A.
83.7
83
N.A.
81
77.2
N.A.
70.8
N.A.
54.1
59.4
N.A.
N.A.
Protein Similarity:
100
98.8
95.4
87.6
N.A.
90.6
89.9
N.A.
91.3
89.5
N.A.
84.2
N.A.
69.1
74.1
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
60
60
N.A.
60
46.6
N.A.
53.3
N.A.
26.6
46.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
73.3
73.3
N.A.
66.6
N.A.
46.6
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
74.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
9
0
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
25
34
9
9
0
0
0
17
92
0
0
% D
% Glu:
0
0
0
0
0
17
9
9
0
0
0
17
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
59
0
0
0
34
0
0
9
0
0
0
0
9
% I
% Lys:
0
34
0
0
0
9
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
25
9
0
0
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
25
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
92
0
0
84
0
% P
% Gln:
25
9
0
0
0
34
0
0
0
0
0
59
0
0
9
% Q
% Arg:
67
9
0
0
9
0
0
0
9
9
0
0
0
0
67
% R
% Ser:
0
0
0
0
0
0
34
59
0
9
0
0
0
0
0
% S
% Thr:
0
25
0
0
0
0
0
17
0
67
0
9
0
0
0
% T
% Val:
0
0
9
92
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
9
0
0
0
92
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _